uwl-280-145
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  Gastric glands in deep mucosa

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Unit_12-10a

1. Gastric glands containing chief and parietal cells

2. Muscularis mucosae

3. Connective tissue in the submucosa

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This image is from an area of the stomach containing gastric glands. These glands (located deep in the lamina propria) empty their products into the bases of the gastric pits.  The deeper portions of the glands contain two types of secretory cells, parietal cells (which produce hydrochloric acid and intrinsic factor) and chief cells (which produce pepsinogen, the inactive form of pepsin).  The parietal cells are large and somewhat triangular in shape with centrally-located, rounded nuclei and pale orange stained cytoplasm.  In contrast, the chief cells tend to be smaller, more rectangular in shape with a pale bluish-purple cytoplasm.

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