* Malaria is caused by the parasite Plasmodium falciparum,
which is transmitted by the female Anopheles mosquito.
* Plasmodium settles in the red blood cells of the human host, where it then
multiplies and hinders erythropoiesis,the making of new red blood cells
*Malaria generally occurs in tropical and subtropical areas. Approximately
40% of the world is at risk, while 80% of cases occur in Africa
Combination fever and chills
* Often, malaria is asymptomatic in the early stages. Symptoms can
also be nonspecific, and difficulty diagnosing is common in
* Some people native to where the disease is prevalent acquire a
natural immunity, however those without any immune defense are the most
at risk for death. For this reason, children who have not yet built an
immunity have the highest fatality rates.
* The disease can greatly damage the nervous system, liver, and kidney.
* Death can occur within hours. Severe outcomes include acute renal
failure, respiratory distress, severe anemia, and death from cerebral
For a description regarding the ways in which
Plasmodium falciparum has adapted to treatments and control techniques