Fungi interact with many organisms. Along with bacteria they have an important role in the ecosystem. Fungi are decomposers of dead plants, animals, and other organic matter. They also release large amounts of carbon dioxide and recycle nitrogen and other nutrients used by plants and other organisms.  There are four ways that Fungi affect humans directly:
1. Mycosis- growing on humans like Aspergillus fumigatus or a yeast infection.  
2. Mycetismus- Mushroom poisoning when eaten. In this case the Deadly Parasol is a great example of this because it is toxic once ingested.
3. Mycotoxicosis- Eating the byproducts of a fungus that are toxic. An example is when you have cheese that is moldy, well most people just cut off the part that had mold on it but little do they know that fungi produce spores which are released all over the cheese and can be toxic.

4. Mycoallergies- Mold allergies.

The Lepiota josserandii has a major interaction with humans. It is one of the many smaller species of the Lepiota genus to cause protoplasmic poisons. Amatoxin syndrome is a fungal toxin that is developed six to twenty four hours after eating the mushroom. Amatoxin is a poison located in the cap and causes low arterial pressure, hepatic coma, and internal bleeding in humans. There also may be a decrease in urine which may be a sign of dehydration or renal failure. You may also be lacking glycogen storage in your blood. People usually die from amatoxin poisoning. Many survive by liver transplants and blood transfers, but for some it's too late. There is no therapy for poisoning.

Abdominal Cramping

Below is the Amatoxin Generic Structure. Amatoxins are oligopeptides synthesized as 35 amino-acids long. The backbone structure is in black and the five group structure is in red. The amatoxins, alpha-, beta-, and gamma-amanitins bind irreversibly to RNA polymerase 2 preventing the transcription of DNA and RNA.




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