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Common name – Botulinum Toxin, BOTOX

Scientific name – Clostridium botulinum

 

Domain -- Bacteria

Kingdom -- Bacteria

Phylum – Firmicutes

Class -- Clostridia

Order -- Clostridiales

Family -- Clostridiaceae

Genus -- Clostridium

Species – Clostridium botulinum

 

Clostridium botulinum belongs to the Domain Bacteria because it is a single-celled organism with no membrane bound organelles except for ribosomes, undergoes cell division by utilizing binary fission, has a single, circular chromosome, and reproduces asexually– all possible characteristics of Bacteria.  Clostridium botulinum is categorized in the Kingdom Bacteria because it has petidoglycan in its cell wall, is a unicellular multiorganism, and does not have a nucleus.  It belongs to the Phylum Firmicutes because it is an obligate anaerobe (does not require air or oxygen to survive) with the ability to produce endospores.  It is a member of the Class Clostridia and the Order Clostridiales because it is spore forming, anerobic, and is a bacillus organism (rod shaped cells).  It is considered to be part of the Genus Clostridium because it is gram-positive, pathogenic, and bacilli-shaped.  Lastly, its species name is Clostridium botulinum because this particular pathogenic species was originally found in blood sausage, and the Latin word for sausage is botulus.

 

Clostridium botulinum is also separated into four groups and seven types depending on chemical and physiological characteristics, as well as susceptibility in species to the toxin.

 

Group

Characteristics

Types

I

Proteolytic, produce high heat resistant spores, minimum growth temperature of 10 degrees C

All type A, and proteolytic strains of types B and F

II

Nonpreoteolytic, produce spores of a low heat resistance, and are capable of grow in low temperatures

All of type E, and nonproteolytic strains of types B and F

III

Nonproteolytic, little known in regards to heat resistance since these strains are not involved in human botulism

All of types C and D strains

 

 

IV

Proteolytic, nonsaccharolytic, with little known of heat resistance of spores

All of type G strains

 

 

 

 

 

 

 

 

Table Table 1 – Produced with information from Louis Smith’s book “Botulism.”

 

Type

Species

Site of Outbreak

A

Humans

United States, U.S.S.R.

B

Humans, Horses

United States, Northern Europe, U.S.S.R.

C

Birds, Turtles, Cattle, Sheep, Horses

Worldwide

D

Cattle, Sheep

Autrailia, South Africa

E

Humans, Birds

Northern Europe, Canada, United States, Japan, U.S.S.R.

F

Humans

Denmark, United States

G

None identified

None identified

 

 

 

 

 

 

Table 2 – Produced with information from Louis Smith’s book “Botulism.”

 

In terms of research done on the different strains of C. botulinum, those that involve the intoxication of humans are by far researched more.

Now that you know all about the classification of C. botulinum, why not learn where it's located compared to other bacteria on the Phylogenetic Tree page.

 

 


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 Author - Phil Strandwitz (strandwi.phil@students.uwlax.edu)

Published April 17th, 2008