Antibiotics are generally used to treat M. pneumoniae infections.  With treatment, full recovery is expected.  It is important to note that penicillin is not used to treat M. pneumoniae infection because of the lack of a cell wall, which penicillin attacks.  Below is a list of the most commonly used antibiotics used to treat M. pneumoniae infection.

 Tetracycline

Å      Administered over a period of one to four weeks

Å      Works by disrupting translation and thereby inhibiting growth

Å      Unsafe to use during pregnancy

Clarithiomycin

Å      Administered over a period of one to two weeks

Å      Works by disrupting translation and thereby inhibiting growth

Å      Safety during pregnancy not established

Erythromycin

Å      Administered over a period of seven to ten days

Å      Works by inhibiting cell growth

Å      Generally safe to use during pregnancy

Azithromycin

Å      Administered over a period of about five days

Å      Generally safe to use during pregnancy

Å      Most common drug used to treat M. pneumoniae infection