The aye-aye is usually found alone and until their mating period, and will rarely interact with any other aye-ayes. The ranges of male and female aye-ayes vary. The male range is generally larger than the females range and can be up to .83 miles squared in area. The females is significantly smaller and is usually about .15 miles squared in area. The range of a male aye-aye will often overlap with the ranges of other male aye-ayes. This causes male aye-ayes to interact with each other on occasion. This is usually when they are competing for a female mate. On the other hand, female ranges do not overlap with any other female and rarely interact with other female aye-ayes.

The aye-aye has only one known predator and it is only a potential predator and does not kill very often. This is the fossa. They are adapted for arboreal movement like the aye-aye. The biggest predator to the aye-aye is the human who sometimes choose to kill it because it is said to bring bad luck to whoever comes upon it.